The "type" of HIFU first determines the depth at which the ultrasonic heat is focused. Equipment commonly used in research has depths of 1.5mm, 3.0mm, and 4.5mm—the shallower depths reach the skin, while deeper depths reach the fascia beneath the skin (the membrane that supports the face)[1]. Which depths are combined depends on the location of sagging (skin laxity) and tissue thickness[1].
What changes with different depths?
Each depth targets a different layer where heat is delivered. 1.5mm targets the skin (dermis), 3.0mm targets the deeper skin, and 4.5mm targets the fascia beneath the skin or neck muscle layers[1].
Broadly speaking, shallow treatment aims for skin firmness and fine lines, while deep treatment aims for tightening from the foundation of the face. Which layer is reached also depends on the treatment location and tissue thickness[1]. Therefore, if the equipment has an imaging function, it becomes easier to select the depth while confirming the target layer[1].
Which depths are actually used with UTIMS A3 varies depending on the treatment facility. Here we explain based on research on HIFU overall.
Does combining depths increase the effect?
Some reports indicate that treatment at two depths produces better results than treatment at a single depth[2]. As the volume and layers of treatment increase, tissue movement and skin firmness scores increased, while pain intensity also increased[2].
In other words, "deeper and more" is not always correct. You decide the balance between the magnitude of change and pain to match your preferences.
In a study of 102 people who received shallow 2.0mm treatment every two weeks for 3 sessions on the eye area, mouth area, and neck lines, wrinkle improvement was observed at 10 weeks and 16 weeks, with no residual side effects[3]. If fine lines are a concern, shallow treatment may be emphasized.
How much change occurs? What about pain?
The change is roughly a "slight tightening." In a trial of 20 people treated with 4.5mm and 3.0mm on the lower face and under the chin, at 3 months, 7 out of 10 people showed clearly noticeable tightening[4].
Pain in the same trial averaged 3.00 on a 10-point scale[4]. Another study found average pain during treatment of 1.79 and after treatment of 0.64, with most resolving within about 2 days[5].
However, the number of studies is still limited. An analysis compiling research on 475 people noted that debate remains about HIFU's effectiveness[6].
HIFU versus high frequency (RF) — which should you choose?
According to guidelines from Japan's Association of Plastic Surgeons, both HIFU and high frequency are effective for sagging (skin laxity) and wrinkles, but their effects fall short of surgery or injections[7]. Scarring is rare with both methods[7].
HIFU's characteristic is that it focuses ultrasound at a single point to target deep layers such as the fascia beneath the skin[1]. High frequency is a different treatment with a different heat delivery method, so which suits you depends on the location and nature of your sagging (skin laxity).
Ultrasonic tightening may take several months to show final results[8]. If you want to time it with an important event, plan ahead or compare other methods.
What should I have examined during the consultation?
You should have examined the location and degree of sagging (skin laxity), the thickness of the skin and tissues beneath it, and whether your concern is "sagging (skin laxity)" or "fine lines." This determines which depths are used and how much treatment is given.
On top of that, confirm which depths will be used with UTIMS A3, pain management measures, and treatment intervals. Since you cannot decide between HIFU and high frequency based on an article alone, have your face examined in person to make an informed decision.
- 1Carruthers J, Burgess C, Day D, Fabi SG, Goldie K, Kerscher M, Nikolis A, Pavicic T, Rho NK, et al. Consensus Recommendations for Combined Aesthetic Interventions in the Face Using Botulinum Toxin, Fillers, and Energy-Based Devices. Dermatologic Surgery. 2016. doi:10.1097/DSS.0000000000000754
- 2Ayatollahi A, Gholami J, Saberi M, Hosseini H, Firooz A. Systematic review and meta-analysis of safety and efficacy of high-intensity focused ultrasound (HIFU) for face and neck rejuvenation. Lasers in Medical Science. 2020. doi:10.1007/s10103-020-02957-9
- 3Han HS, Park JW, Kim SY, Yoo KH, Choi SY, Kim BJ. Safety and efficacy of high-intensity focused ultrasound for treatment of periorbital, perioral, and neck wrinkles: Prospective open single-center single-arm confirmatory clinical trial. Dermatologic Therapy. 2022. doi:10.1111/dth.15420
- 4Zhu J, Han Y, Liu Y, Chang R, Gao W, Gong X, Zhu Y, Shang Y, Shen L, et al. Evaluation of a Novel Microfocused Ultrasound with Three-Dimensional Digital Imaging for Facial Tightening: A Prospective, Randomized, Controlled Trial. Dermatology and Therapy. 2023. doi:10.1007/s13555-023-01078-9
- 5Li X, Xie GH, Yang Z, Li S, Liao X, Lu J, Jiang X, Li K, Xie S, et al. Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments: Efficacy and Safety. Aesthetic Plastic Surgery. 2026. doi:10.1007/s00266-025-05205-z
- 6Modena DAO, Ferro AP, Rangon FB, Guirro ECO. Systematic review and meta-analysis - microfocused ultrasound treatment for sagging skin. Lasers in Medical Science. 2025. doi:10.1007/s10103-025-04424-9
- 7Japan Association of Plastic Surgeons, Special Issue, Vol. 44 Supplement. CQ2-1-2 Wrinkle and sagging (skin laxity) treatment with high-frequency (RF), CQ2-1-3 High-intensity focused ultrasound (HIFU) treatment (both recommendation level 2 - weakly recommended. Effects do not match surgical or injection treatments, but scarring is rare).
- 8Shridharani SM, Ribaudo JG, Kennedy ML. Skin Tightening Technologies in Body Contouring. Plastic and Reconstructive Surgery. 2025. doi:10.1097/PRS.0000000000012005