Stem Cell Therapy
An anti-aging treatment that harnesses the regenerative power of stem cells derived from your own fat to fundamentally improve deep wrinkles, Sagging (skin laxity), and volume loss.
Recommended for
- Ideal for those concerned about deep wrinkles or sagging cheeks, finding hyaluronic acid and botox insufficient
- Those wishing to improve skin quality itself and maintain youthful skin over the long term
- Those not desiring surgical Facelift but seeking comprehensive regenerative anti-aging
- Those seeking safe, self-tissue-based treatment and concerned about allergies and rejection responses
What is Stem Cell Therapy?
Stem cell therapy (stem cell treatment) is a regenerative medicine procedure in which mesenchymal stem cells (ADSCs: Adipose-Derived Stem Cells) harvested from the patient's own adipose tissue are cultured, concentrated, and reinjected into the skin and facial tissues. Stem cells are special cells possessing "self-renewal capacity" and "multi-differentiation potential." After administration, they differentiate into skin cells and collagen-producing cells while secreting abundant growth factors (VEGF, EGF, IGF-1, etc.) that activate surrounding tissues.
Adipose-derived stem cells differ from ES cells (embryonic stem cells) and iPS cells in that they carry extremely low ethical concerns and tumor risk. Since they use the patient's own tissue, there is no rejection response. In a joint statement published by IFATS (International Federation of Adipose Therapeutics and Science) and ISCT (International Society for Cellular Therapy) in 2013 (Cytotherapy journal), mesenchymal stem cells derived from adipose tissue are positioned as a promising cellular source in regenerative medicine.
Scientific Evidence: Skin Regeneration Mechanism via Growth Factors
Paracrine factors secreted by mesenchymal stem cells play a central role in skin regeneration. A study published in PLOS ONE (2008) demonstrated that bone-marrow-derived MSCs abundantly secrete VEGF-α, EGF, IGF-1, and keratinocyte growth factor, recruiting macrophages and vascular endothelial cells to promote wound healing (doi: 10.1371/journal.pone.0001886).
Additionally, exosomes (extracellular vesicles) derived from adipose stem cells promote fibroblast migration, proliferation, and collagen synthesis in a dose-dependent manner, as reported in Scientific Reports (2016, doi: 10.1038/srep32993). Furthermore, a study in the Journal of Translational Medicine (2015, doi: 10.1186/s12967-015-0417-0) confirmed that MSC-derived exosomes promote wound closure and enhance collagen synthesis and angiogenesis. These findings demonstrate that stem cell therapy extends beyond simple cell transplantation to create a "rejuvenation environment" throughout the tissue.
Treatment Flow
① Consultation & Blood Tests: Pre-treatment blood tests are performed to screen for infections. We will discuss your treatment areas and goals in detail.
② Fat Harvesting (Mini Liposuction): Under local anesthesia, a small amount (approximately 20–50 ml) of fat is harvested from inconspicuous areas such as the abdomen or thighs. The incision is only a few millimeters, leaving virtually no scarring.
③ Stem Cell Culture & Expansion (Approximately 4–6 Weeks): Stem cells (ADSCs) are isolated and cultured from the harvested adipose tissue, then expanded to the necessary cell count. Culturing is performed at a CPC (cell processing center) approved by domestic medical institutions.
④ Administration: Concentrated stem cells are administered via injection or infusion to areas of concern such as wrinkles, Sagging (skin laxity), or volume loss. Injections use ultra-fine needles to minimize discomfort.
Downtime & Recovery Period
The fat harvesting site may experience mild bruising and swelling in the days following treatment, but in most cases this subsides within 1–2 weeks. Swelling at the injection site (face, etc.) typically lasts a few days to 1 week. Results are usually noticed gradually over 1–3 months following injection, peaking around 6 months, with effects tending to persist long-term. Hospitalization is not required, and most patients can return to desk work the following day.
Ideal Candidates
Those concerned about deep wrinkles or Sagging (skin laxity) that are difficult to improve with hyaluronic acid or botox
Those wishing to fundamentally improve skin quality and maintain youthful skin long-term
Those seeking comprehensive anti-aging with minimal downtime
Those wishing to avoid surgical procedures (such as Facelift) but seeking reliable regenerative results
Features
Zero Rejection Because It Uses Your Own Cells
Since stem cells are harvested from your own fat, there is no risk of allergic reactions or immune rejection. Unlike ES cells and iPS cells, there are no ethical concerns, and this safe regenerative medicine is advancing in research both domestically and internationally.
Growth Factors Fundamentally Improve Skin Environment
Growth factors such as VEGF, EGF, and IGF-1 secreted by stem cells promote collagen production, angiogenesis, and cell proliferation in a synergistic manner. Rather than "filling in" like hyaluronic acid injection, this is a fundamental approach that enhances the skin's own regenerative capacity.
Long-term Rejuvenation via Exosomes
Exosomes (extracellular vesicles) released by stem cells activate fibroblasts and continuously promote Type I and III collagen synthesis (Scientific Reports, 2016). Effects emerge gradually over 6 months post-injection and persist long-term.
Addresses Deep Wrinkles & Volume Loss
While botox is effective for facial expression muscles and hyaluronic acid for shallow wrinkles, stem cell therapy promotes regeneration of the skin tissue itself, making it effective for areas difficult to treat with conventional injection therapies—such as deep wrinkles, hollow cheeks, and under-eye hollowing.
Pricing
Stem Cell Therapy
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※ All prices include tax.
FAQ
When can I expect to see results from stem cell therapy?
Within the first few weeks after administration, growth factors begin activating tissue, and many patients notice improved collagen production and skin firmness. Peak effects typically occur 3–6 months post-injection, after which results tend to persist long-term. Since results vary individually, we recommend checking progress with your doctor as treatment progresses.
ZetithAIに続けて聞く →What is the difference between stem cell therapy and hyaluronic acid injection?
Hyaluronic acid is a "filling" procedure that adds substance to the skin to create volume, with effects lasting several months to a year before being absorbed. Stem cell therapy involves administering your own cells to establish a "regenerative environment" in the skin, promoting collagen production and angiogenesis, thereby allowing expectations of fundamental improvement in deep wrinkles, skin quality, and long-term persistence. Since the two serve different purposes, they can also be combined.
ZetithAIに続けて聞く →Is fat harvesting painful? How much downtime is there?
Fat harvesting is performed under local anesthesia, so pain during the procedure is minimal. After harvesting, you may experience mild muscle soreness or bruising for 1–3 days, but in most cases this resolves naturally within 1–2 weeks. Since the harvested amount is small (20–50 ml), the burden on the body is minimal, and in most cases you can return to desk work the next day.
ZetithAIに続けて聞く →How do I book a consultation or make an appointment?
Please make reservations via LINE or phone. At your initial consultation, your doctor will discuss your current concerns, goals, and medical history in detail to determine whether stem cell therapy is optimal for you. You can also consult about combining this with other treatments.
ZetithAIに続けて聞く →Consultations about this treatment are free.
Book / free consult via LINE
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