Fat X Core (Fat-dissolving injection)

A minimally invasive injectable body-contouring treatment that breaks down and eliminates fat cells through the cell membrane-disrupting action of deoxycholic acid, with minimal downtime

Recommended for

  • Patients concerned with localized fat bulging in areas such as double chin, abdomen, thighs, and upper arms
  • Patients who prefer to avoid surgical liposuction and seek body-contouring treatment with minimal downtime
  • Patients struggling with stubborn localized fat that does not diminish despite continued exercise and dietary restrictions
  • Patients aiming for fundamental fat cell reduction without recurrence

What is Fat X Core (Fat-dissolving injection)?

Fat X Core is a non-surgical body-contouring treatment in which an injectable formulation containing deoxycholic acid (DOC) as the main ingredient is directly injected into localized subcutaneous fat layers to physically and chemically destroy and eliminate fat cells. Unlike surgical procedures (liposuction), its greatest advantage is that partial fat reduction can be achieved using only injections without a scalpel.

Deoxycholic acid is a type of bile acid and a naturally occurring surfactant derived from the body. A 2004 study published in Dermatologic Surgery (Rotunda et al.) demonstrated that deoxycholic acid's surfactant activity (cell membrane dissolution) is the primary driver of the fat-dissolving effect of phospholipid injection formulations (doi: 10.1111/j.1524-4725.2004.30305.x). Based on this finding, injection-dissolution therapy has become clinically established as a powerful treatment option for localized fat.

Mechanism of action

The injected deoxycholic acid acts on the cell membrane of fat cells, destroying the membrane's integrity. As the cell membrane dissolves, lipids inside the cells flow out of the cell, and the fat cells undergo necrosis and disappear. Subsequently, through the body's natural metabolic process (phagocytosis by macrophages and excretion via lymphatic vessels), the destroyed cells and free fatty acids are expelled from the body over the course of several weeks.

A clinical report published in the 2006 Aesthetic Surgery Journal (Hasengschwandtner et al.) demonstrates that injection-dissolution therapy for localized fat is effective as an alternative to surgical liposuction, with confirmed fat-reduction effects in multiple areas including the abdomen, submental region, and knee area (doi: 10.1016/j.asj.2006.01.008). A temporary inflammatory response occurs after injection, which is part of the process that promotes remodeling and excretion of adipose tissue.

Treatment flow

After determining the target area and injection volume during consultation, the skin at the treatment site is disinfected. Using ultra-fine injection needles, the formulation is evenly injected into the fat layer. Treatment time varies depending on the area but typically takes 10–20 minutes per site. After injection, light massage may be performed to distribute the formulation evenly.

Swelling, redness, warmth, and bruising may occur at the injection site for several days immediately after treatment. This is an inflammatory response indicating that the formulation is working normally and typically subsides within 1–2 weeks. Results vary from person to person, but generally, changes become noticeable after 1–2 treatments, and more significant improvement is expected with multiple treatments. The recommended interval between treatments is 4–6 weeks.

Downtime and precautions

Swelling peaks around 2–4 days after treatment. Face washing and showering are possible from the day of treatment. Please refrain from bathing (in a bath), strenuous exercise, and alcohol consumption for 24–48 hours after treatment. Practice thorough sun protection and avoid rubbing or massaging the injection site forcefully. Bruising, if present, will fade within 1–2 weeks.

Features

Non-surgical, scalpel-free fat dissolution

Since fat reduction in localized subcutaneous areas can be achieved with injections alone, downtime is shorter compared to liposuction surgery, minimizing the impact on daily life.

Natural excretion using bio-derived ingredients

Deoxycholic acid is a substance derived from bile acid that naturally exists in the body. Fat cells that are destroyed are slowly expelled through the body's natural metabolic pathways, avoiding sudden systemic changes.

Fine adjustments suitable for localized fat reduction

Injections can be precisely targeted to specific areas such as double chin, abdomen, thighs, hip lower region, and upper arms—localized fat that is difficult to reduce through exercise alone. The ability of the practitioner to make detailed design adjustments is a key feature.

Sustained improvement through multiple treatments

Since fat cells that have been dissolved and eliminated do not regenerate, sustained results can be expected with proper lifestyle maintenance. Gradual, repeated treatments yield more natural results.

Pricing

Treatment Price (incl. tax)
1cc
  • Regular¥22,000
10cc
  • Regular¥99,000

※ All prices include tax.

FAQ

How many treatments are typically needed?

The number varies depending on your concerns and fat thickness, but generally, 2–4 treatments performed at 4–6 week intervals tend to produce visible results. Some patients notice changes after just one treatment, but multiple treatments are recommended for more significant improvement. During your initial consultation, your physician will propose an appropriate treatment plan.

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How is this different from liposuction?

Liposuction is a surgical procedure that can remove a large amount of fat at once, but it requires general anesthesia and incisions, with downtime potentially extending several weeks. In contrast, fat-dissolving injection treatment can be performed with injections alone, minimizing impact on daily life. However, fat reduction per session is less than with liposuction, and multiple treatments are necessary. Liposuction is better suited for cases requiring early removal of large volumes of fat over a wide area, whereas injection-dissolution therapy may be more appropriate for patients concerned with mild to moderate localized fat.

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Can I return to work immediately after treatment?

Swelling and redness may occur for several days immediately after treatment. If your work involves frequent public-facing contact, it is reassuring to plan 2–3 days after treatment. Most patients return to desk work the following day. For facial treatments (such as double chin), where swelling is more noticeable, we sometimes recommend scheduling before a holiday period.

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Where can I make a reservation?

Reservations are available via LINE or phone. For first-time visitors, please first book a consultation appointment, during which your physician will explain the treatment area, number of sessions, and treatment plan in detail. Please feel free to contact us.

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Consultations about this treatment are free.

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